Get it configured properly and it will go a very long way towards protecting your enterprise. If you can afford a decent firewall appliance with virus checking. I have appliances on my network edge that catch the bulk of virus, malware and phishing type threats. If you're safe with your computer but just want some reassurance, go that route. Downloaded Eicar but within a few seconds it removed eicar test file from downloads folder. It didn't detected while it should cause it's a eicar malware. So, now I downloaded the eicar test file (look it up it's authentic test file) Malwarebytes didn't detected anything, I even scanned the various eicar test files manually with Malwarebytes. Downloaded intentional crack file to check, Malwarebytes didn't detected, Sophos did and removed - I agree it can be false positive. For everyone, got the Malwarebytes premium trial.
If illegal software downloads are what you're after (such as a cracked version of Photoshop), you WILL get burned eventually.